Providing biological solutions for industrial problems SYNBIOCHEM is housed in the Manchester Institute of Biotechnology (MIB), a leading UK/EU industry-interfaced biotechnology institute and widely acknowledged beacon of interdisciplinary bioscience. Our SynBio research focus for Industrial Biotechnology (IB) and chemicals manufacture at Manchester has a major role to play in delivering the UK’s vision for the bio-based economy, especially in bio-based chemicals manufacture, bio-therapeutics and novel bio-materials.
Our D/B/T/L technology platforms are underpinned with in-depth chemical expertise/understanding and coupled to RRI. We can offer access to our computational design tools, novel parts (enzymes/regulatory tools), Build/Test platforms, methodologies and “know-how” and have interdisciplinary expertise to help address your industrial challenges.
Collaborative Research: Current industry collaborations range from UK Research Council funded Industrial Partnering Awards (IPA) and sLola projects, EU consortium awards, major direct industry funded programs and short proof of concept grants. Examples include:
- Biosynthesis of semi-synthetic antibiotics
- Development of industrial chemicals through synthetic biology and pathways engineering
- Microbial cell factories for the production of high value pharmaceuticals
- New methods for the rapid directed evolution of enzymes and synthetic microorganisms for the development of industrial biocatalysts
Research Commercialisation: Translation of our research activities is a key mark of our success. Recent patents from SYNBIOCHEM investigators (often through working in partnership with industry) include:
- New single-step SynBio/fermentative production routes to the cholesterol lowering drug pravastatin
- Novel cascade biocatalytic approaches for the production of chiral amines
- New routes to biosynthetic menthols and gaseous biofuels (propane)
Spin outs: Since inception in 2006, the MIB has formed eight spin out companies C4X Discovery, Bioshape, PeptiGelDesign, Spectromics, Reacta Biotech, PharmaKure, Discovery Biocatalysts and the recently formed C3 Biotechnology.
Benefits of working with us include:
- Access to leading facilities and expertise
- Interdisciplinary portfolio of research and expertise to meet your company’s specific needs
- Innovation transfer from laboratory towards manufacturing processes.
- Direct licensing of technologies and processes
- Access to funding for academic research partnerships unavailable to commercial projects
SYNBIOCHEM Training for industry: We were pleased in 2016 to welcome new CASE and industry funded PhD students working on projects on the development of: next generation bio-fuels; high throughput screening and assembly platforms for SynBio; and business models and strategies for the commercialisation of disruptive technologies.
National Networks for Industrial Biotechnology and Bioenergy: The Centre works closely with NIBB including BIOCATNET, BioProNET, IBCarb and NPRONET (led by members of the MIB). These provide platforms for open discussions with research institutes and industry.
Work with us: We are always interested in hearing from new potential partners. For further details of collaboration and partnership opportunities please contact: Dr Kirk Malone: Kirk.Malone@manchester.ac.uk T: +44(0)161 306 0245