Responsible Research and Innovation

The Responsible Research and Innovation (RRI) platform is developing major programmes on the ethical and regulatory aspects faced by SynBio, which includes real-time assessment and anticipation of research and innovation trajectories, deliberation and reflection, and collaborative development.

SYNBIOCHEM - Responsible Research Innovation

The RRI Group seeks to initiate early RRI dialogue, provide expertise, guidance and training in responsible governance of SynBio innovation, and foster public engagement and training for the research community.

Responsible Innovation – The Centre is fostering processes and dialogue to help researchers, industry, policymakers, NGOs and other stakeholders to anticipate the benefits and risks of SynBio early on in the scientific and innovation journey and feed this into decision-making, i.e. how to deliver products and processes that are commercially viable and societally useful.

Ethical and Social Factors – The Centre is analysing the ethical and social factors contributing to innovation with appropriate public engagement anticipating both the intended and the potential for unintended impacts in the use and commercial development of new discoveries.

The pathways to market will encounter issues at all stages of the SynBio process and require new and appropriate regulation and governance. Lessons taken from other areas of innovation (e.g. use of GMOs) demonstrate the importance of anticipating and addressing ethical and social issues relating to new technologies at an early stage, to ensure adequate public engagement, to anticipate issues, and to feed back into decision-making.

Governance and Policy – SynBio emergence raises global and national governance and regulatory issues aspect from discovery through proof of principle to market. The Centre will engage with regulatory and governance issues, including working with policy stakeholders, companies, researchers, non-profits, and others to deliberate on, and develop and implement, responsible approaches.

Recent Events and Workshops

open-dayResponsible Research and Innovation: End to End Assessment Pop Up. Everyday practices involving menthol products formed the theme of a stall run by the SYNBIOCHEM Responsible Research and Innovation RRI Group at the Manchester Institute for Biotechnology Open Day on 18th November 2016.  Andy Balmer, Robert Meckin and Barbara Ribeiro ran the pop-up stall — and they have written up a SYNBIOCHEM RRI on what happened and what was learned, see: 16-02-menthol-mib-popup-2016-11

Women in Science was the theme of a workshop and discussion facilitated by theWISE-Thumb SYNBIOCHEM RRI Group at the Manchester Institute of Biotechnology on the 27th April, 2016. The workshop considered key challenges involved in bringing about equality for women within science, technology, engineering and medicine, with a focus on industrial biotechnology and synthetic biology. The workshop encouraged the discussion of personal experiences. Workshop participants reflected on some practical changes that participants and others could make to help decrease structural and everyday impediments to equality.WiSE 2016WiSE 2016


Making Sense of Methol. Robert Meckin. March 2017. [blog]

Shaking things up with RRI. Barbara Ribeiro – Profile. November 2016. [MIOIRBlog]

Synthetic Biology’s Second World by Andrew Balmer. Discusses the closed doors meeting at Harvard on the prospect of synthesising the human genome, which has caused something of a stir. See PlosBlog weblink

Sally Randles  reports from the Virtual Institute of Responsible Innovation (VIRI), held in San Sebastian in March 2016. [Read More]

IMG_0691Selected Publications:

  • Synthetic Biology: A Sociology of Changing Practices. Basingstoke: Palgrave MacMillan. Balmer, A. S., Bulpin, K., & Molyneux-Hodgson, S. (2016).10.1057/9781137495426. Publication link: 1ab2c01e-c2b0-4d14-ace4-69920f865395 | DOI:10.1057/9781137495426
  • Responsibility Navigator – Sally Randles and The Res-AGorA EU FP7 funded project have co-constructed a good-practice framework, the “Responsibility Navigator”, with practitioners and strategic decision-makers. The framework facilitates reflective processes involving multiple stakeholders and policy-makers with the generic aim of making EU research and innovation more responsible, responsive and sustainable (Kuhlmann et al.)

Training and Awareness – The RRI Group assists the Centre to provide training for:

  1. Industry/academics to learn state-of-the-art SynBio technology
  2. Academics/SMEs to understand the regulatory context and societal impact of SynBio
  3. Educating the next generation of SynBio researchers and managers in interdisciplinary and strategic skills
  4. Developing opportunities for the general public to access information and engage in deliberation about advances in SynBio

Select for RRI Group Members